L-Tyrosine — Neurotransmitter Support for Focus Under Pressure
L-Tyrosine — Neurotransmitter Support for Focus Under Pressure
Found in: Focus by Of The Gods
L-Tyrosine is a conditionally essential amino acid and the direct biochemical precursor to dopamine, norepinephrine, and epinephrine — the catecholamine neurotransmitters that drive focus, motivation, and executive function. While the body can synthesize tyrosine from phenylalanine, supplementation becomes particularly valuable during periods of acute cognitive demand, stress, or sleep deprivation, when catecholamine stores are rapidly depleted.†
Biochemical Profile & Mechanism of Action
L-Tyrosine participates in a well-characterized biosynthetic cascade:
- L-Tyrosine → L-DOPA (via tyrosine hydroxylase — the rate-limiting step)
- L-DOPA → Dopamine (via aromatic amino acid decarboxylase)
- Dopamine → Norepinephrine (via dopamine β-hydroxylase)
- Norepinephrine → Epinephrine (via phenylethanolamine N-methyltransferase)
Under stress, the brain accelerates catecholamine turnover. Supplemental L-Tyrosine replenishes the substrate pool, preventing the cognitive decline that accompanies neurotransmitter depletion.†
Research-Supported Benefits
- Cognitive resilience under stress: A systematic review of randomized controlled trials concluded that tyrosine supplementation reliably counteracts the decline in cognitive function induced by physical stress, cold exposure, and sleep deprivation (Jongkees et al., 2015).†
- Working memory: Tyrosine supplementation improved performance on demanding working memory tasks (N-back) in a double-blind, placebo-controlled crossover study in healthy adults (Colzato et al., 2013).†
- Military performance: In U.S. military research, tyrosine (150 mg/kg) prevented the cognitive and mood deterioration caused by sustained wakefulness and cold stress, with significant effects on vigilance, reaction time, and mood (Mahoney et al., 2007).†
- Multitasking: A study found that tyrosine promoted cognitive flexibility — the ability to switch between mental tasks — a key component of executive function (Steenbergen et al., 2015).†
Why It's in Focus
L-Tyrosine addresses the neurochemical side of focus: ensuring the brain has adequate raw material for dopamine and norepinephrine synthesis during demanding cognitive work. It works synergistically with L-Theanine (which modulates the calming GABA system) and Lion's Mane (which builds neural architecture), creating a full-spectrum approach to sustained cognitive performance in Focus.†
Scientific References
- Jongkees, B. J., Hommel, B., Kühn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands — A review. Journal of Psychiatric Research, 70, 50–57. doi:10.1016/j.jpsychires.2015.08.014
- Colzato, L. S., Jongkees, B. J., Sellaro, R., & Hommel, B. (2013). Working memory reloaded: tyrosine repletes updating in the N-back task. Frontiers in Behavioral Neuroscience, 7, 200. doi:10.3389/fnbeh.2013.00200
- Mahoney, C. R., Castellani, J., Kramer, F. M., Young, A., & Lieberman, H. R. (2007). Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiology & Behavior, 92(4), 575–582. doi:10.1016/j.physbeh.2007.05.003
- Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50–55. doi:10.1016/j.neuropsychologia.2015.01.022
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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from 29 reviewsBeen a long time imbiber. Love the switch to monk fruit sweetened vs Axe-K….less sweet and better flavor. On its own, mixed with a little chai, or even in an Americano, Focus is my morning go-to to steer my morning in a productive, engaged direction
My partner and I live and die by this, really can't have our coffee without it anymore. My partner says his focus and memory have never been better after using this for a couple months and we don't get the coffee jitters/anxiety when we have this. Definitely can feel the difference from when we use it vs don't use it. Love love love!!
Finally, a mushroom based product where I know the how much I am getting from each major supplement. On top of that, this tastes great and fits into my morning routine. I'm glad they offered me a discount for the subscription plan!
This stuff tastes amazing. It tastes just like cocoa powder but also gives me a sense of alertness, but without the jitters that too much caffeine can give.I recommend adding it in milk (or water, both are great) to make a hot cocoa type drink.
Great product with amazing flavor and friendly customer service.
I started putting this supplement in my morning coffee and noticed a pretty big difference in how long I felt energy throughout the day as well as a pretty big reduction in anxiety. My coffee just isn't the same without it now.
I hate mushrooms. I had no idea it was made from mushrooms! I love this stuff! Gove it a try!
Tried this for the first time at a farmers market and it tasted so good as hot chocolate. Great way to incorporate mushrooms that have so many health benefits.
Ive been using it for two weeks now and with my daily busy schedule, this supplement is a way to go powder with all my favorite drinks in the morning! My daily cup of coffee/ hot chocolate and even added it in my protein shake.
While having a great taste, it also enhanced immune health to reducing stress to better mental clarity and focus!
Of the Gods made me feel great during my morning routine! The taste was amazing in my hot chocolate too! I’m hyped about this product!
Had this product at a Christmas market today and it was so so so yummy!! My husband and I both loved it. I found the effect quite calming and it reduced my headache. We met the founders and they were cool people! They know their stuff when it comes to science and ingredients. 10/10 brand, company and product. Would recommend!
I've been taking reishi mushrooms for years, and Of The Gods is by far the best tasting mushroom supplement I've ever tried. I love that they are transparent about the amount of each ingredient in the bottle, which really sets them apart. The quality and flavor are unmatched, and it's now my go-to choice for mushroom supplements!
My wife and I drink it every morning mixed into hot water.
I love this product! I tend to get bored of the same old morning drink and so I’m always on the lookout for products that taste delicious but are also healthy. I started drinking OTG almost a year ago and it’s absolutely delicious! I’m not a fan of synthetic flavoring but I find OTG to be very well balanced and temperate. When I add it to my coffee in the morning or my smoothies in the afternoon, I find the taste to be more complimentary than over-powering. OTG is also delicious on it own, which is great when I need a change. It’s similar to a healthy hot chocolate! SO good! It gives me a gentle boost in the morning to start my day. I would highly recommend this product for a healthy addition to your diet.
This supplement has a delicious creamy chocolatey flavor and is rich and smooth in taste. It really worked to stabilize my energy level. You didn't get that rush then crash that you get with coffee. A great way to start your morning!
Amazing taste & service
Been a long time imbiber. Love the switch to monk fruit sweetened vs Axe-K….less sweet and better flavor. On its own, mixed with a little chai, or even in an Americano, Focus is my morning go-to to steer my morning in a productive, engaged direction
My partner and I live and die by this, really can't have our coffee without it anymore. My partner says his focus and memory have never been better after using this for a couple months and we don't get the coffee jitters/anxiety when we have this. Definitely can feel the difference from when we use it vs don't use it. Love love love!!
Finally, a mushroom based product where I know the how much I am getting from each major supplement. On top of that, this tastes great and fits into my morning routine. I'm glad they offered me a discount for the subscription plan!